2013 Publications
Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4.
Authors: Kim Y, Spitz GS, Veturi U, Lach FP, Auerbach AD, Smogorzewska A.
Blood, 2013.
Kerfuffle: a web tool for multi-species gene colocalization analysis.
Authors: Aboukhalil R, Fendler B, Atwal GS.
BMC Bioinformatics, 2013.
Impact of constitutional copy number variants on biological pathway evolution.
Authors: Poptsova M, Banerjee S, Gokcumen O, Rubin MA, Demichelis F.
BMC Evolutionary Biology, 2013.
Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration.
Authors: Thorvaldsdóttir H, Robinson JT, Mesirov JP.
Briefings in Bioinformatics, 2013.
Authors: Béguelin W, Popovic R, Teater M, Jiang Y, Bunting KL, Rosen M, Shen H, Yang SN, Wang L, Ezponda T, Martinez-Garcia E, Zhang H, Zheng Y, Verma SK, McCabe MT, Ott HM, Van Aller GS, Kruger RG, Liu Y, McHugh CF, Scott DW, Chung YR, Kelleher N, Shaknovich R, Creasy CL, Gascoyne RD, Wong KK, Cerchietti L, Levine RL, Abdel-Wahab O, Licht JD, Elemento O, Melnick AM.
Cancer Cell, 2013.
Authors: Demichelis F, Garraway LA, Rubin MA.
Cancer Cell, 2013.
A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition.
Authors: Whittaker SR, Theurillat JP, Van Allen E, Wagle N, Hsiao J, Cowley GS, Schadendorf D, Root DE,Garraway LA.
Cancer Discovery, 2013.
Oncogenic Activation of Pak1-Dependent Pathway of Macropinocytosis Determines BCG Entry into Bladder Cancer Cells.
Authors: Redelman-Sidi G, Iyer G, Solit DB, Glickman MS.
Cancer Research, 2013.
Punctuated evolution of prostate cancer genomes.
Authors: Baca SC, Prandi D, Lawrence MS, Mosquera JM, Romanel A, Drier Y, Park K, Kitabayashi N, Macdonald TY, Ghandi M, Van Allen E, Kryukov GV, Sboner A, Theurillat JP, Soong TD, Nickerson E, Auclair D, Tewari A, Beltran H, Onofrio RC, Boysen G, Guiducci C, Barbieri CE, Cibulskis K, Sivachenko A, Carter SL, Saksena G, Voet D, Ramos AH, Winckler W, Cipicchio M, Ardlie K, Kantoff PW, Berger MF, Gabriel SB, Golub TR, Meyerson M, Lander ES, Elemento O, Getz G, Demichelis F, Rubin MA, Garraway LA.
Cell, 2013.
Lessons from the cancer genome.
Authors: Garraway LA, Lander ES.
Cell, 2013.
Genome-wide chromatin state transitions associated with developmental and environmental cues.
Authors: Zhu J, Adli M, Zou JY, Verstappen G, Coyne M, Zhang X, Durham T, Miri M, Deshpande V, De Jager PL, Bennett DA, Houmard JA, Muoio DM, Onder TT, Camahort R, Cowan CA, Meissner A, Epstein CB, Shoresh N, Bernstein BE.
Cell, 2013.
Authors: Wilkinson AC, Ballabio E, Geng H, North P, Tapia M, Kerry J, Biswas D, Roeder RG, Allis CD, Melnick A, de Bruijn MF, Milne TA.
Cell Reports, 2013.
Phase II trial of MEK inhibitor selumetinib (AZD6244) in patients with BRAFV600E/K-mutated melanoma.
Authors: Catalanotti F, Solit DB, Pulitzer MP, Berger M, Scott SN, Iyriboz T, Lacouture ME, Panageas K, Wolchok JD, Carvajal RD, Schwartz GK, Rosen N, Chapman PB.
Clinical Cancer Research, 2013.
BEND6 is a nuclear antagonist of Notch signaling during self-renewal of neural stem cells.
Authors: Dai Q, Andreu-Agullo C, Insolera R, Wong LC, Shi SH, Lai EC.
Development, 2013.
Authors: Miura P, Shenker S, Andreu-Agullo C, Westholm JO, Lai EC.
Genome Research, 2013.
Authors: Wang R, Islam K, Liu Y, Zheng W, Tang H, Lailler N, Blum G, Deng H, Luo M.
Journal of the American Chemical Society, 2013.
Authors: Kwan WH, van der Touw W, Paz-Artal E, Li MO, Heeger PS.
The Journal of Experimental Medicine, 2013.
An H3K36 Methylation-Engaging Tudor Motif of Polycomb-like Proteins Mediates PRC2 Complex Targeting.
Authors: Cai L, Rothbart SB, Lu R, Xu B, Chen WY, Tripathy A, Rockowitz S, Zheng D, Patel DJ, Allis CD, Strahl BD, Song J, Wang GG.
Molecular Cell, 2013.
The n-SET Domain of Set1 Regulates H2B Ubiquitylation-Dependent H3K4 Methylation.
Authors: Kim J, Kim JA, McGinty RK, Nguyen UT, Muir TW, Allis CD, Roeder RG.
Molecular Cell, 2013,
Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.
Authors: Efeyan A, Zoncu R, Chang S, Gumper I, Snitkin H, Wolfson RL, Kirak O, Sabatini DD, Sabatini DM.
Nature, 2013.
Fanconi anaemia and the repair of Watson and Crick DNA crosslinks.
Authors: Kottemann MC, Smogorzewska A.
Nature, 2013.
The mutational landscape of adenoid cystic carcinoma.
Authors: Ho AS, Kannan K, Roy DM, Morris LG, Ganly I, Katabi N, Ramaswami D, Walsh LA, Eng S, Huse JT, Zhang J, Dolgalev I, Huberman K, Heguy A, Viale A, Drobnjak M, Leversha MA, Rice CE, Singh B, Iyer NG, Leemans CR, Bloemena E, Ferris RL, Seethala RR, Gross BE, Liang Y, Sinha R, Peng L, Raphael BJ, Turcan S, Gong Y, Schultz N, Kim S, Chiosea S, Shah JP, Sander C, Lee W, Chan TA.
Nature Genetics, 2013
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation.
Authors: Morris LG, Kaufman AM, Gong Y, Ramaswami D, Walsh LA, Turcan ª, Eng S, Kannan K, Zou Y, Peng L, Banuchi VE, Paty P, Zeng Z, Vakiani E, Solit D, Singh B, Ganly I, Liau L, Cloughesy TC, Mischel PS, Mellinghoff IK, Chan TA.
Nature Genetics, 2013.
Authors: Fritz EL, Rosenberg BR, Lay K, Mihailoviæ A, Tuschl T, Papavasiliou FN.
Nature Immunology, 2013.
Authors: Gaudet MM, Kuchenbaecker KB, Vijai J, Klein RJ, Kirchhoff T, et al.
PLoS Genetics, 2013.
Pattern discovery and cancer gene identification in integrated cancer genomic data.
Authors: Mo Q, Wang S, Seshan VE, Olshen AB, Schultz N, Sander C, Powers RS, Ladanyi M, Shen R.
Proceedings of the National Academy of Sciences of the USA, 2013.
Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia.
Authors: Wang E, Kawaoka S, Yu M, Shi J, Ni T, Yang W, Zhu J, Roeder RG, Vakoc CR.
Proceedings of the National Academy of Sciences of the USA, 2013.
Highly Recurrent TERT Promoter Mutations in Human Melanoma.
Authors: Huang FW, Hodis E, Xu MJ, Kryukov GV, Chin L, Garraway LA.
Science, 2013.
Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma.
Authors: Lewis PW, Müller MM, Koletsky MS, Cordero F, Lin S, Banaszynski LA, Garcia BA, Muir TW, Becher OJ, Allis CD.
Science, 2013.

