First Starr Cancer Consortium Grant Competition

(in alphabetical order by principal investigator)

"Translational Studies of Neural Mechanisms of Chemotherapy-induced Cognitive Changes"

Principal Investigator:

  • Tim Ahles, PhD, Memorial Sloan-Kettering Cancer Center

Co-Principal Investigator:

  • David Silbersweig, MD, Weill Medical College of Cornell University

"Mechanism of tumor progression in mouse and human familial GIST"

Principal Investigator:

  • Peter Besmer, PhD, Memorial Sloan-Kettering Cancer Center

Co-Principal Investigator:

  • Michael Wigler, PhD, Cold Spring Harbor Laboratory
  • Cristina Antonescu, MD, Memorial Sloan-Kettering Cancer Center
  • Joseph Scandura, MD, PhD, Weill Medical College of Cornell University

"Epithelial Stem Cells in Lung Cancer and COPD"

Principal Investigator:

  • Ronald G. Crystal, MD, Weill Medical College of Cornell University

Co-Principal Investigator:

  • Malcolm A.S. Moore, DPhil, Memorial Sloan-Kettering Cancer Center

"Discovering Small Molecule Inhibitors of MYC and RAS"

Principal Investigator:

  • Todd R. Golub, MD, The Broad Institute of Harvard & MIT

Co-Principal Investigators:

  • Michael A. Foley, PhD, The Broad Institute of Harvard & MIT
  • Derek S. Tan, PhD, Memorial Sloan-Kettering Cancer Center

"Comparative oncogenomics to discover oncogene synthetic lethality"

Principal Investigator:

  • William C. Hahn, MD, PhD, The Broad Institute of Harvard & MIT

Co-Principal Investigators:

  • Gary Gilliland, MD, PhD, The Broad Institute of Harvard & MIT
  • Greg Hannon, PhD, Cold Spring Harbor Laboratory
  • Scott Lowe, PhD, Cold Spring Harbor Laboratory

"Identification of Subclasses of Cerebellar Granule Neuron Progenitor Cells, and their Potential to form Pediatric Brain Tumors"

Principal Investigator:

  • Mary E. Hatten, PhD, Rockefeller University

Co-Principal Investigator:

  • Linda Van Aelst, PhD, Cold Spring Harbor laboratory

"Application of Genomics to Developmental Therapeutics of Melanoma"

Principal Investigator:

  • Alan N. Houghton, MD, Memorial Sloan-Kettering Cancer Center

Co-Principal Investigators:

  • Levi Garraway, MD, PhD, The Broad Institute of Harvard & MIT
  • Todd R. Golub, MD, The Broad Institute of Harvard & MIT
  • Scott Powers, PhD, Cold Spring Harbor Laboratory
  • Neal Rosen, MD, PhD, Memorial Sloan-Kettering Cancer Center
  • Gary Schwartz, MD, Memorial Sloan-Kettering Cancer Center

"Design and application of biocompatible dendrimers for cancer therapy"

Principal Investigator:

  • Samie Jaffrey, MD, PhD, Weill Medical College of Cornell University

Co-Principal Investigator:

  • David Gin, PhD, Memorial Sloan-Kettering Cancer Center

"Role of Alternative Splicing in Regulating Cancer-Cell Metabolism"

Principal Investigator:

  • Adrian Krainer, PhD, Cold Spring Harbor Laboratory

Co-Principal Investigator:

  • Lewis Cantley, PhD, The Broad Institute of Harvard & MIT

"Tumor development and treatment of EBV-associated lymphomas in immune competent humanized mice"

Principal Investigator:

  • Christian Munz, PhD, Rockefeller University

Co-Principal Investigator:

  • Ethel Cesarman, MD, PhD, Weill Medical College of Cornell University

"Breast Cancer Protective Alleles by Whole Genome Association and Copy Number Analysis"

Principal Investigator:

  • Kenneth Offit, MD, Memorial Sloan-Kettering Cancer Center

Co-Principal Investigators:

  • David Altshuler, MD, PhD, The Broad Institute of Harvard & MIT
  • Daniel Haber, MD, PhD, The Broad Institute of Harvard & MIT

"Testing and Validating High Throughput Analysis of FFPE Samples: Transforming the Scope of Investigations into the Genomic Basis of Cancer"

Principal Investigator:

  • Scott Powers, PhD, Cold Spring Harbor Laboratory

Co-Principal Investigators:

  • William Gerald, MD, PhD, Memorial Sloan-Kettering Cancer Center
  • Robert Lucito, PhD, Cold Spring Harbor Laboratory
  • Adam Olshen, PhD, Memorial Sloan-Kettering Cancer Center
  • Agnes Viale, PhD, Memorial Sloan-Kettering Cancer Center

"Dendritic Cell Targeting: A Novel Approach to Tumor Vaccination"

Principal Investigator:

  • Jeffrey Ravetch, MD, PhD, Rockefeller University

Co-Principal Investigators:

  • Ralph Steinman, MD, Rockefeller University
  • Alan Houghton, MD, Memorial Sloan-Kettering Cancer Center
  • James Allison, PhD, Memorial Sloan-Kettering Cancer Center

"Targeting the cancer stem cell niche for novel cancer therapeutics"

Principal Investigator:

  • Stuart Schreiber, PhD, The Broad Institute of Harvard & MIT

Co-Principal Investigators:

  • David Scadden, MD, The Broad Institute of Harvard & MIT
  • Gary Gilliland, MD, PhD, The Broad Institute of Harvard & MIT
  • Malcolm Moore, DPhil, Memorial Sloan-Kettering Cancer Center

"The Sarcoma Genome Project Phase II: A Comprehensive Molecular Characterization of Soft Tissue Sarcoma to Identify Subtype Specific Therapies"

Principal Investigator:

  • Samuel Singer, MD, Memorial Sloan-Kettering Cancer Center

Co-Principal Investigators:

  • Chris Sander, PhD, Memorial Sloan-Kettering Cancer Center
  • Marc Ladanyi, MD, Memorial Sloan-Kettering Cancer Center
  • Thomas Tuschl, PhD, Rockefeller University
  • Matthew Meyerson, MD, PhD, The Broad Institute of Harvard & MIT

"Mechanisms of miRNA biogenesis and mRNA targeting and molecular interventions to modulate miRNA pathways in normal and disease states"

Principal Investigator:

  • Thomas Tuschl, PhD, Rockefeller University

Co-Principal Investigators:

  • Dinshaw Patel, PhD, Memorial Sloan-Kettering Cancer Center
  • Eric Holland, MD, PhD, Memorial Sloan-Kettering Cancer Center
  • Hakim Djaballah, PhD, Memorial Sloan-Kettering Cancer Center